Wednesday, August 10, 2011

Large Computer, Distributed Cluster or Amazon Cloud?

A very popular comment in seqanswers forum starts with -

Hello – I use to think I was good with a computer
I wonder how many people are in the same boat as me.

1) Institute bought a couple of GAIIs
2) No one has money to use them
3) Institute has internal competition to pay for a couple of runs (makes the donors feel better about their donation if someone uses the machines), and you are lucky enough to get funded
4) You send a couple of samples off to never-never land and someone sends back a terabyte drive or two with “next-gen sequencing data”
5) You quickly realize people that use to do survival curves in your bioinformatics core don’t really know that Illumina fastq is different from Sanger fastq and the analysis they provide is limited at best
5) Now what do you do?


Please continue here

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